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Interstitial Lung Disease and Obstructive Sleep Apnea

Study Purpose

Clinically, all patients with interstitial lung disease were observed, and relevant clinical data were collected. Bronchoscopic specimens were collected according to the condition of the enrolled patients, and the ROSE smear was evaluated, combined with the NGS results of these patients. To observe the etiology and biological characteristics of exacerbation in patients with interstitial lung disease. Patients with apnea should be tested for polysomnography, and corresponding biological specimens should be obtained for molecular biology or other tests

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

No
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Observational
Eligible Ages 18 Years - 80 Years
Gender All
More Inclusion & Exclusion Criteria

Inclusion criteria:

  • - over 18 years old and under 80 years old.
  • - Clinical diagnosis of interstitial lung disease or obstructive respiratory sleep apnea syndrome.
  • - Patient is conscious and capable of signing informed consent.
  • - The patient may wear a polysomnograph.

Exclusion criteria:

  • - malignant tumors.
  • - severe heart failure.
  • - uremia.
  • - autoimmune diseases.
  • - pulmonary embolism, and end-stage chronic obstructive pulmonary disease.
  • - Patients with mental illnesscannot sign informed consent on their own.

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT05838183
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Dan Liu
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

N/A
Principal Investigator Affiliation N/A
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Other
Overall Status Recruiting
Countries China
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

ILD OSA
Arms & Interventions

Arms

: OSA group

Sleep detection was performed in OSA patients,And according to the severity of the analysis, obtain the corresponding biological specimens, the relevant detection

: Interstitial lung disease group

Bronchoscopy was performed to obtain alveolar lavage fluid in ILD patients and lung tissue was obtained for ROSE and NGS in appropriate patients

Interventions

Diagnostic Test: - The relationship between imaging and ROSE and NGS

The correlation between ROSE and NGS in imaging and bronchoscopy of ILD patients was observed

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

International Sites

Tianjin, China

Status

Recruiting

Address

Tianjin Medical University General Hospital

Tianjin, , 300000